Literature summary extracted from

Siomos, M.F.; Badrinath, A.; Pasierbek, P.; Livingstone, D.; White, J.; Glotzer, M.; Nasmyth, K.
Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans (2001), Curr. Biol., 11, 1825-1835.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.22.49	Rec8 + H2O	Saccharomyces cerevisiae	-	cleaved Rac8	-	?
3.4.22.49	Rec8 + H2O	Caenorhabditis elegans	-	cleaved Rac8	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.49	Caenorhabditis elegans	-	-	-
3.4.22.49	Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.22.49	Rec8 + H2O	-	Saccharomyces cerevisiae	fragments of Rac8	-	?
3.4.22.49	Rec8 + H2O	-	Caenorhabditis elegans	fragments of Rac8	-	?
3.4.22.49	Rec8 + H2O	-	Saccharomyces cerevisiae	cleaved Rac8	-	?
3.4.22.49	Rec8 + H2O	-	Caenorhabditis elegans	cleaved Rac8	-	?

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Release 2023.1 (January 2023)